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August 13, 1982

New criteria for diagnosing SLE

JAMA. 1982;248(6):622. doi:10.1001/jama.1982.03330060004002

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In a report concerned with diagnostic criteria for systemic lupus erythematosus (SLE), Eng M. Tan, MD, head of the Division of Rheumatic Diseases at the University of Colorado School of Medicine, Denver, presented the proposed 1982 revision of preliminary 1971 criteria for classification of the disease.

Speaking for himself and eight co-investigators from various areas of the country, Tan said that the revision incorporates new information about SLE from serological and immunopathological studies, increases sensitivity (the ability to detect sick persons), and improves or retains specificity (the ability to rule out well persons).

He added that the criteria, revised at the request of the American Rheumatism Association in 1979, emerged from a study incorporating data on more than 340 SLE patients and control subjects (patients with other forms of arthritis). Each SLE patient was paired with the next age-, sex-, and racially matched patient with an inflammatory rheumatic disease who