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August 13, 1982

Spontaneous Retroperitoneal Hemorrhage From Renal Carcinoma

JAMA. 1982;248(6):720-721. doi:10.1001/jama.1982.03330060060036

SPONTANEOUS retroperitoneal hemorrhage from the kidney is rare. Although hemorrhage may occur after trauma to a normal kidney, spontaneous rupture of the kidney is usually associated with some underlying structural abnormality and has occurred with infection, hydronephrosis, and benign and malignant tumors.

Four patients have been treated for adenocarcinoma of the kidney that presented with spontaneous retroperitoneal hemorrhage. The diagnostic evaluation and treatment of these patients are presented.

Report of Cases  Four patients manifested symptoms prompted by retroperitoneal hemorrhage from renal cell carcinomas. Each patient had sudden abdominal or flank pain or the exacerbation of preexisting pain of recent onset develop. There was no history of trauma in any patient. Leukocytosis developed in each case, and fever was present in patients 1 and 2. Patient 3 had a recent episode of phlebitis and was receiving anticoagulation therapy with warfarin sodium. The clinical presentation, radiological studies, treatment, and outcome in each