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July 27, 1994

Fundamental Immunology

JAMA. 1994;272(4):320-321. doi:10.1001/jama.1994.03520040082051

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The first great revolution in immunology is credited to Louis Pasteur. Among the many achievements stemming from that early period is the elimination of smallpox from the entire world in 1977, a century later. The second great revolution, beginning with immunochemistry in the 1940s, is ongoing. Perhaps our counterparts a century from now will be pleased with the outcome. This elegant textbook explains what is going on in immunology today and where it may lead us. Could any outcome, a century from now, be as impressive as the elimination of smallpox?

The editor, Dr William Paul, is a physician and a scientist at the National Institute of Allergy and Infectious Diseases. Recently he was appointed director of AIDS research, an important and prestigious office. Dr Paul has a fine national reputation as a senior lecturer and teacher of remarkable fluency and clarity. He and his coworkers have devised not a

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