The person with diabetes is more likely to be obese than is his nondiabetic peer. Similarly, there is a greater probability of diabetes occurring in an obese person. It is assumed frequently, therefore, that the two are related causally. However, as O'Sullivan points out in this issue of The Journal (p 949), there is a dearth of prospective data on this common problem.
O'Sullivan has, since 1954, studied groups of women who received prenatal care at Boston City and Boston Lying-In hospitals. Those whose glucose tolerance was abnormal during pregnancy, but who had a normal postpartum oral glucose tolerance test (OGTT) result, had subsequent development of diabetes more frequently than did women who had normal OGTT results during pregnancy. The increased risk for women with transient gestational diabetes for development of diabetes later in life is, of course, well recognized.1 The new analysis of the data, in terms of body
Horwitz DL. Diabetes and Obesity. JAMA. 1982;248(8):976–977. doi:10.1001/jama.1982.03330080058031
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