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September 3, 1982

Recurrence and Heterogeneity in Painless Thyrotoxic Lymphocytic Thyroiditis: Report of Five Cases

Author Affiliations

From the Division of Endocrinology, Lutheran Medical Center (Dr Taylor); the Department of Medicine, Case Western Reserve University School of Medicine (Dr Taylor); and the Department of Endocrinology, The Cleveland Clinic Foundation (Dr Sheeler), Cleveland.

JAMA. 1982;248(9):1085-1088. doi:10.1001/jama.1982.03330090055029

Five patients had recurrent episodes of spontaneously resolving thyrotoxicosis (SRT). Three displayed only the classic low-uptake variety of this disorder, while two had alternating episodes of high-uptake and low-uptake thyrotoxicosis. Two of the three with low uptake only who had thyrotropin displacement activity (TDA) assays had negative results on this test, while one of the patients with alternating high- and low-uptake thyrotoxicosis had a positive TDA assay result, suggesting that the pathogenesis in the two types of SRT may differ.

(JAMA 1982;248:1085-1088)