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May 12, 1989

AIDS and the Nervous System

Author Affiliations

Dartmouth Medical School Veterans Administration White River Junction, Vt

Dartmouth Medical School Veterans Administration White River Junction, Vt

JAMA. 1989;261(18):2719. doi:10.1001/jama.1989.03420180145052

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This monograph represents the most current and comprehensive account to date of the neurological disorders associated with the acquired immunodeficiency syndrome (AIDS). The core of this account is the personal clinical and pathological experience of the editors, based on their observations of a remarkable number (1286) of AIDS patients. In addition, the editors have enlisted contributions from 35 eminent investigators, each of whom has written authoritatively on some aspect or aspects of the neurology of AIDS.

The volume comprises five main subjects, each of which is considered in intimate detail: The first subject is the neuroepidemiology of AIDS. The data presented by the authors are impressive and frightening. It is estimated (conservatively) that in 1991, there will be 74 000 new cases of AIDS and 54 000 deaths from the disease—making it the fourth commonest cause of death in the United States, after heart disease, cancer, and stroke. Clinically, neurological