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June 23, 1989

Animals in Research

JAMA. 1989;261(24):3602-3606. doi:10.1001/jama.1989.03420240116037

WITHIN this century, spectacular advances have been made in the prevention, diagnosis, and treatment of many diseases. With expansion of our basic knowledge of processes involving biochemistry, physiology, and molecular biology, important new directions in medicine have been taken. Although medicine requires research for the development of new thought, the research process itself is less well understood. The brief glossary herein, which is organized to provide ready access to diseases and/or disciplines, cites some of the most important new discoveries in medicine and their bases. The list is not meant to be exhaustive, and research crucial to certain fields is omitted. Its purpose is to emphasize the research process and to point out the mechanisms by which answers often are obtained. The theme presented within the glossary is the indispensability of animals in research, often because animals and humans suffer from many of the same diseases. In fact, much of