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To the Editor.—
Chonmaitree et al, in "The Clinical Relevance of 'CSF Viral Culture': A Two-Year Experience With Aseptic Meningitis in Rochester, NY" (1982;247:1843), found that the highest yield of positive viral cultures in young infants with clinical and laboratory findings of meningitis occurred in the summer and fall months. They estimated a 70-day reduction in antibiotic therapy and in hospitalization during a two-year period at Strong Memorial Hospital, Rochester, NY.Two colleagues and I, following methodology similar to that used in the article, recently completed a study in which we reviewed the charts of patients who had CSF viral cultures at Columbia-Presbyterian Medical Center (CPMC), New York. While we found the highest yield of positive cultures in patients with the same profile as in the study of Chonmaitree et al, the influence of viral CSF cultures was drastically different.During the four-year interval 19771981, more than 350 CSF viral
King DK. 'CSF Viral Cultures'. JAMA. 1982;248(12):1450–1451. doi:10.1001/jama.1982.03330120020014
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