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October 1, 1982

Sonographically Guided Fine-Needle Aspiration of Liver Lesions

JAMA. 1982;248(13):1639-1641. doi:10.1001/jama.1982.03330130087037

FINE-needle percutaneous aspiration biopsy of the liver and other intraabdominal organs has been shown to be a safe and accurate method for the cytological diagnosis of cancer.1-4 When combined with an imaging modality such as ultrasound, computed tomography, or fluoroscopy, the diagnostic yield has been reported to be from 85% to 100%.1-4 The liver is easily depicted sonographically. With present-day ultrasound equipment, lesions as small as 2 cm can be imaged. Since 1978 the radiologists in this group of authors have used ultrasound as a guide in aspirating focal masses in the liver. This method has provided rapid and accurate diagnoses in 45 of 59 patients, thus eliminating other more costly and time-consuming studies.

Materials and Methods  The chief indication for performing a guided percutaneous thin-needle aspiration was the demonstration of a focal solid or semisolid liver mass on an initial diagnostic scan (Figure). Before the aspiration biopsy