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September 1, 1989

Transplantation of Abdominal Viscera-Reply

Author Affiliations

University of Pittsburgh (Pa)

University of Pittsburgh (Pa)

JAMA. 1989;262(9):1184. doi:10.1001/jama.1989.03430090045017

In Reply. —  We concur with Dr Davison that patient 1 in our report was too ill to have survived, even with a perfect operation. This was evident in retrospect, since the autopsy findings reported in our article included diagnoses not established prospectively. No one who saw this beautiful child could resist the instinct to save her.Concerning the comments by Drs Lantos and Kohrman, the procedures were done with the approval of the institutional review board of the Children's Hospital of Pittsburgh. The protocols were exhaustively reviewed, along with the informed consent.The use of related transplant procedures to treat extensive upper abdominal tumors described by Goldsmith1 was reported before the American Surgical Association in April 1989 and discussed by Moore,2 whose advice and comments throughout the years have been unfailingly wise and supportive. Eight of the latter 10 adult recipients are alive after 3 to 9 months,