[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.204.52.4. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
October 6, 1989

Immunotherapy and Asthma-Reply

JAMA. 1989;262(13):1773. doi:10.1001/jama.1989.03430130046024

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

In Reply.—  In our article, we tried to demonstrate that most patients with severe asthma can be managed with highdose oral corticosteroids. We do not recommend use of oral steroids initially if imminent respiratory failure or a questionable ability of the patient to absorb the medications through the gastrointestinal tract is considered.There were no statistical differences between either group as related to treatment with antibiotics, use of subcutaneous terbutaline or inhaled atropine, or prior use of steroids. Of the 11 patients who received prior steroids, 8 of them had received 10 mg or less in the prior 24 hours. The inclusion or exclusion of the remaining 3 patients, 1 of whom was in the intravenous group, did not alter the results of the study. Perhaps, as Dr Bogin pointed out, the patient who fails to respond to aggressive outpatient therapy with high-dose oral medication should receive intravenous corticosteroids. It,

×