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October 22, 1982

Screening for Cognitive Impairment

Author Affiliations

University Hospitals Cleveland

JAMA. 1982;248(16):1975. doi:10.1001/jama.1982.03330160027017

To the Editor.—  In the editorial by DePaulo entitled "Psychiatric Morbidity From Long-term Medications" (1982;247:1867), he recommends the use of standardized and structured examinations to identify and quantitate psychopathological and cognitive impairment. While we fully agree with this approach, we would caution that the information obtained from two of these instruments, the Cognitive Capacity Screening Examination (CCSE)1 and the Mini-Mental State Examination (MMSE),2 might be different.To date, we have used these screening tests on 25 patients with a variety of CNS degenerative diseases, including Parkinson's disease, Huntington's disease, and Alzheimer's dementia. None of these patients had clouding of consciousness at the time of examination. They ranged in age from 19 to 82 years (mean, 66.2 years). The two tests were administered on separate occasions, in random sequence, and usually within a three-month interval.