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November 5, 1982

Controversial Practices in Allergy

Author Affiliations

Mobile, Ala

JAMA. 1982;248(17):2113. doi:10.1001/jama.1982.03330170021010

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To the Editor.—  In regard to an article by Michael H. Grieco, MD, JD, entitled "Controversial Practices in Allergy" (1982;247:3106), I will confine my remarks to the intradermal provocative-neutralizing method. The technique described by Grieco was abandoned almost 20 years ago. The technique used effectively today is described in my book, Food Allergy: Provocative Testing and Injection Therapy (Charles C Thomas Publisher, 1972).The communication by Grieco indicated that the positive test results of my double-blind study were followed by "four controlled studies [that] were unable to support the efficacy of this method." In fact, all of these negative study results preceded my positive results, and none of these findings were concerned with my subject.The Kailin-Collier study, reported only in a letter published in The Journal, attempted to determine the validity of symptom neutralization testing. However, the physician was not allowed to see the wheals! His choice of neutralizing