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November 12, 1982

Pregnancy After Gliosis Uteri (Endometrii)

JAMA. 1982;248(18):2311-2313. doi:10.1001/jama.1982.03330180071040

PROLIFERATION of fetal neural tissue in the endometrium or endocervix occurs rarely. Since the entity was first described by Orsos1 in 1934, fewer than 30 cases have been verified. Glial tissue in the uterus has been reported using the following various terms to describe what probably represents the same entity: glial polyp,2glioma of the uterus,3gliomatosis uteri,4glial tissue in the uterus,5 and proliferatingglia in the endometrium.6 We prefer Bazala's term gliosis uteri,7 which describes a benign condition that may persist or recur locally.2 The condition, as theorized by most authors, probably results from a homograft of fetal glial stroma.

We recently had the opportunity to care for a patient with persistent gliosis uteri (endometrii) who wanted to conceive another child. We reviewed the pertinent literature to secure information on fertility subsequent to this problem. To our knowledge, no pregnancies after