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February 11, 1983

Severe Metabolic Complications in a Cross-Country Runner With Sickle Cell Trait

Author Affiliations

From the Departments of Internal Medicine (Drs Helzlsouer and Hayden), Pathology (Dr Hayden), Pediatrics (Dr Rogol), and Pharmacology (Dr Rogol), the University of Virginia School of Medicine, Charlottesville.

JAMA. 1983;249(6):777-779. doi:10.1001/jama.1983.03330300061037

A 17-year-old black male with sickle cell trait collapsed after completion of a 5,000-m cross-country race. He manifested CNS dysfunction, disseminated intravascular coagulation, rhabdomyolysis, renal insufficiency, and deep venous thrombosis. Sickle cell crisis may have been etiologic in the pathogenesis of this constellation of abnormalities.

(JAMA 1983;249:777-779)