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March 18, 1983

Evaluation of Hemangiomas With Technetium 99m—Labeled RBCs: The Perfusion—Blood Pool Mismatch

Author Affiliations

From the Departments of Nuclear Medicine (Drs Front and Israel), Ear, Nose, and Throat (Drs Joachims and Eliachar), and Radiology (Dr Brown), Rambam Medical Center and Technion Faculty of Medicine, Haifa, Israel.

JAMA. 1983;249(11):1488-1490. doi:10.1001/jama.1983.03330350064032

HEMANGIOMAS are benign tumors composed of blood vessels that contain a large volume of blood. In capillary hemangiomas, the majority of the vessels that make up the tumor have the caliber of normal capillaries, while cavernous hemangiomas are distinguished for their large, cavernous vascular spaces. There are, however, capillaries among the cavernous channels, and, in fact, there is no clear line of distinction between the capillary and cavernous forms.1 When found on the skin or membranes of the oral cavity, hemangiomas have a characteristic appearance and do not pose a diagnostic problem. Hemangiomas, however, also appear in internal organs, eg, liver and spleen, and in bone, orbit, nasopharynx, and subepiglottis,2 where diagnosis may be less straightforward.3,4 Skull roentgenograms and even angiography may fail to diagnose hemangiomas of the mandible,5 and computed tomography is not always characteristic of orbital hemangiomas.6,7 The diagnostic problem becomes especially important