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April 1, 1983

Malignant Neoplasms Occurring After Cardiac Transplantation

Author Affiliations

From the Department of Cardiac Surgery (Mr Lanza and Drs Cooper and Barnard) and Renal Unit (Dr Cassidy), Groote Schuur Hospital; and University of Cape Town Medical School (Mr Lanza and Drs Cooper, Cassidy, and Barnard), Cape Town, South Africa.

JAMA. 1983;249(13):1746-1748. doi:10.1001/jama.1983.03330370056032

Fifty-seven cardiac transplants in 53 patients have been performed; 30 survived for at least three months. Malignant neoplasms developed in three (10%) of these patients. This incidence is more than double that in recipients of donor kidneys at our institution. Kaposi's sarcoma developed in three patients in the combined groups and accounted for 30% of all malignant neoplasms. The possible reasons for these high incidences are discussed.

(JAMA 1983;249:1746-1748)