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April 8, 1983

The Pathophysiology of Human Immunologic Disorders

Author Affiliations

Institute of Pathology Case Western Reserve University Cleveland

JAMA. 1983;249(14):1933-1934. doi:10.1001/jama.1983.03330380097043

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This volume is not a textbook of clinical immunology in the usual sense. It deals with immunologic mechanisms and is meant for readers with a good foundation in immunobiology who wish to gain some clinical perspective or update their information in areas of human immunology other than their own.

The book is divided into 12 chapters written by 17 authors, a sign of the times and the explosion in the field. Some of the topics include "Disorders of B Lymphocytes," "Macrophages and Immune Regulation," "Immunodeficiencies," "Immune Complexes," "T-Cell Differentiation," "Immunology of Aging," and "Immunobiology of Cancer and Lymphoid Neoplasms."

The most objectionable aspects of the book are those that could have been very easily corrected. All chapters are variably plagued by typographic errors and misspellings of words and sometimes of names of authors. In addition, literature references are frequently wrong or discrepant with the text as to the year of