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June 17, 1983

Physiological Responses to Burning Injury

Author Affiliations

The University of Chicago Medical Center

JAMA. 1983;249(23):3252. doi:10.1001/jama.1983.03330470072041

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


As Davies aptly points out in his preface, the last 20 years have seen an almost logarithmic increase in the numbers of published reports concerning the physiological responses to the burn injury and its treatment. Davies' extensive review of the current state of knowledge of the pathophysiology of thermal trauma represents a helpful and important accomplishment. This is even more impressive because this is not a multiauthored survey but a review by a single author.

Extensive burns are probably the most severe form of trauma a human can sustain, and they affect virtually every physiological and biochemical system. Davies surveys these effects in a well-organized manner, beginning with those events and changes that occur immediately after burning and proceeding temporarily to those that occur up to three weeks after being burned. This review has extensive citations, and most of the material has been published in the last 30 years.