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July 1, 1983

The Febrile Child: Clinical Management of Fever and Other Types of Pyrexia

Author Affiliations

University of Florida at Jacksonville

JAMA. 1983;250(1):90-91. doi:10.1001/jama.1983.03340010070040

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Thanks are due to Martin I. Lorin, MD, associate professor of pediatrics at Baylor College of Medicine, author of this superior treatise on fever, for using the Fahrenheit scale with centigrade values in parentheses throughout. The book is logically organized, with one third dealing with pathophysiology, the middle portion with clinical relevance, and the last part with symptomatic therapy.

With a semihard cover and pleasant type and margins, the book has extensive references and an adequate index. One feels that Dr Lorin has exhaustively reviewed the English literature on the subject of fever in preparing the test.

The current concept of why fever develops in mammals is explained. The thermoregulatory center of the brain located in the preoptic region of the anterior hypothalamus (POAH) has a "set point" that acts as a stabilizer. By far the most common modifier of the set point is endogenous pyrogen, a substance released by