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October 7, 1983

Indium 111 takes dead aim at inflammation, abscesses

JAMA. 1983;250(13):1658-1662. doi:10.1001/jama.1983.03340130004003

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Indium 111 continues to appear useful in the detection of inflammatory processes, according to reports presented at the recent annual meeting of the Society of Nuclear Medicine in St Louis. The radioactive compound indium 111 chloride (111InCl3) may be especially effective in the diagnosis of osteomyelitis and may have clinical advantages over gallium citrate Ga 67 for the detection of suspected abscesses.

The study suggesting the applicability of111InCl3 to the detection of osteomyelitis was conducted by Bettye Sayle, MD, George Cierney, MD, Jon Mader, MD, and Donna Wilkey, MD, of the University of Texas Medical Branch, Galveston. Fifty-eight patients with suspected osteomyelitis first underwent technetium Tc 99m bone scans and then were injected with 3mCu of111InCl3 preparatory to imaging with a gamma camera. Some of the patients underwent Ga 67 scanning a week later. All resulting scintigrams were correlated with the results