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November 11, 1983


Author Affiliations

Marshfield Clinic Marshfield, Wis

JAMA. 1983;250(18):2553. doi:10.1001/jama.1983.03340180097046

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The nine years that elapsed between publication of the third and fourth editions of this book have witnessed many advances in our understanding and treatment of human leukemias. This progress is reflected in the fourth edition. The number of contributors has increased from six to 26, all of whom have been active in leukemia research. The multiauthored format results in a book containing authoritative chapters at the expense of uniform style and some overlap among chapters. In some instances, a topic is discussed in part in several different chapters (eg, terminal deoxynucleotidyl transferase), when the information would be more easily digested if presented in a single section.

The book has been reorganized with larger sections devoted to areas where recent progress has occurred. The etiology of leukemia has been expanded from a portion of one chapter to an entire section with six chapters, including an important chapter on retroviruses and