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December 2, 1983

Atopic Dermatitis—A New Therapeutic Regimen

JAMA. 1983;250(21):2926-2927. doi:10.1001/jama.1983.03340210024009

To the Editor.—  The Primer on Allergic and Immunologic Diseases (1982; 248:2611) of Nov 26, 1982, discusses atopic dermatitis as an allergic manifestation, which is contrary to a recent statement in the seventh edition of Andrews'Diseases of the Skin, edited by Domonkos and colleagues,1 published in 1982. According to the opinion of these authoritative dermatologists regarding atopic dermatitis: "Identification of the allergens, their elimination, and hyposensitization to the offending substances, have been the principal methods of study and management of this disease. Clinically this approach has been remarkably unrewarding." My own personal experience coincides with this statement.A revolution in the etiologic concept and therapeutic management of atopic dermatitis occurred at the October 1963 meeting of the Los Angeles Dermatological Society when Jud R. Scholtz, MD, introduced a new regimen based on findings by Sulzberger and associates2,3 that atopic dermatitis was associated with a defect in the patient's