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June 28, 1995

Thrombosis and Hemorrhage

JAMA. 1995;273(24):1962-1963. doi:10.1001/jama.1995.03520480082050

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This is the first edition of a multiauthored text on hemostasis and clinical disorders of blood clotting and thrombosis. The first third of the book is divided into three major sections: coagulation and fibrinolysis, platelets, and the vessel wall. Each chapter in these sections is an indepth discussion of a specific aspect of physiologic hemostasis and includes the molecular biology, biology, and biochemistry of clotting factors, platelets, and endothelial cells. The information is very detailed and could be used as a definitive reference on the structure and function of all important molecules and cells that support or inhibit hemostasis.

The text is supported by excellent diagrams and tables. There are good-quality color plates of megakaryocytes but minimal scanning or transmission electron micrographs. One of the major deficits of this basic section of the book is the absence of an initial detailed overview of both primary and secondary hemostasis, including endothelial

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