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January 13, 1984

Multiple Sclerosis: Pathology, Diagnosis and Management

Author Affiliations

Boston University

JAMA. 1984;251(2):265-266. doi:10.1001/jama.1984.03340260069035

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The literature of multiple sclerosis is distinguished by several features: it is enormous; it is multidisciplinary, venturing into the fields of virology, immunology, clinical neurophysiology, neuropathology, experimental pathology, and psychology, to name just a few; it is controversial; and it has, unfortunately, led to little new in our understanding of its pathogenesis or etiology. Because of these problems, it is necessary from time to time, to attempt to collate, codify, and, if possible, clarify this vast amount of published and unpublished material.

The authors of this latest attempt are eminently qualified to do just what is necessary and have assembled a group of experts from many centers to try to bring order to the chaos. The amount of information contained in this book is truly stupendous and it can unquestionably be called a state-of-the-art compendium. Many points of view are represented, many theories are discussed with candor and erudition, but