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January 13, 1984

Neurological Complications of Therapy: Selected Topics

Author Affiliations

University of Utah Medical Center Salt Lake City

JAMA. 1984;251(2):266. doi:10.1001/jama.1984.03340260070037

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This multiauthored volume represents a collection of reviews of neurological complications resulting from medical and surgical therapies. The editor has carefully chosen chapters that address those neurological complications commonly encountered in day-to-day neurological consultative practice.

The untoward effects of medications on the CNS receive the greatest attention in this volume and include those associated with chemotherapeutic agents, antibiotics, cardiovascular medicines, anticonvulsants, and others. Discussions of complications of cancer chemotherapeutic agents, antibiotics, antiparkinsonism drugs, and anticoagulants are particularly current and concise, with excellent bibliographies. The chapter on anticonvulsants is organized by reversible and nonreversible effects, a format that does not allow quick and easy reference to a particular drug's toxicity; in addition, some anticonvulsants, such as valproic acid, receive little or no attention. The discussion of complications of tranquilizers and hypnosedatives could benefit from a fuller consideration of the side effects of major tranquilizers. The chapters dealing with complications due to