To the Editor.—
I refer to the article entitled "The Prognostic Value of Ambulatory Blood Pressures" by Perloff and co-workers1 in a recent issue of The Journal. The authors seem to have uncovered a valuable prognostic indicator for the assessment of subsequent morbidity and mortality in younger patients having mild to moderate hypertension. Furthermore, it seems instinctively attractive to be able to evaluate a patient's level of hypertension out in the "real world" rather than during an emotionally laden visit to the physician's office.I do, however, have some concerns with the methodology of this study. It would have been valuable to have examined the predictive value of ambulatory blood pressure when all other relevant factors were adjusted or controlled. Although the authors do adjust their findings for age, severity, sex, and prior treatment individually, they fail to examine the predictive value of ambulatory blood pressure when all of
Grossman N. Prognostic Value of Ambulatory Blood Pressures. JAMA. 1984;251(3):344. doi:10.1001/jama.1984.03340270026022
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