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Article
August 14, 1991

Management of Hypertensive Crises

Author Affiliations

From the Department of Hypertension and Nephrology, The Cleveland (Ohio) Clinic Foundation.

From the Department of Hypertension and Nephrology, The Cleveland (Ohio) Clinic Foundation.

JAMA. 1991;266(6):829-835. doi:10.1001/jama.1991.03470060091033
Abstract

The availability of potent antihypertensive drugs that will decrease markedly elevated blood pressure within minutes to hours has changed the concepts of definition and therapy of hypertensive emergencies and urgencies. Intravenous infusion of sodium nitroprusside can be used in the truly emergent situation and is effective, reliable, and safe. While oral therapy is more convenient, it is not as consistently effective as parenteral administration and can lead to excessive reductions in blood pressure that are more difficult to manage than when short-acting agents are given intravenously.

(JAMA. 1991;266:829-835)

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