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February 17, 1984

Delivery of a Healthy Infant Following Nonsurgical Ovum Transfer

Author Affiliations

Division of Reproductive Endocrinology Department of Obstetrics and Gynecology Harbor-UCLA Medical Center Torrance, Calif
Fertility and Genetics Research, Inc Chicago

JAMA. 1984;251(7):889. doi:10.1001/jama.1984.03340310011002

To the Editor.—  We wish to announce the birth of a healthy infant to an infertile nulligravid woman following nonsurgical recovery and transfer of an in vivo fertilized donated ovum.1,2The infertile recipient, a woman in her 30s with an eight-year history of infertility and multiple operations for endometriosis, experienced a spontaneous luteinizing hormone (LH) peak two days prior to the donor. The donor was a healthy, fertile woman who matched the recipient couple for blood type and Rh and hair and eye color. On the day of the LH peak, the donor was inseminated with semen from the recipient's husband. Five days later uterine lavage was performed on the donor. The recovered blastocyst was transferred to the uterus of the infertile woman. Six days later, beta human chorionic gonadotropin was detected in the recipient's serum. Thirty-three days after the transfer, pelvic ultrasound revealed a well-developed uterine sac with