We thank Drs Katz and Weiss for elaborating on the epidemiology and diagnosis of condyloma and their relationship to HPV. We agree entirely that the NDTI data on the incidence of condyloma acuminatum are minimum estimates of sexually transmitted HPV infections. If we were to add the diagnoses of flat condyloma, cervical intraepithelial neoplasia (CIN), and other genital neoplasms to the spectrum of HPV lesions, the incidence would be much greater. Thus, we concur that HPV is a very common—and probably the most neglected—sexually transmitted infection.Even though the NDTI data minimized both the spectrum and the magnitude of HPV infections, we believe that they accurately reflect trends of condyloma acuminatum during the past 15 years. They demonstrate that the incidence of HPV lesions has dramatically increased. This rise is consistent with trends in other STDs, such as genital herpes and Chlamydia trachomatis, for which we have inadequate
Cates W, Alexander ER, Becker TA. Diagnosis and Epidemiology of Condyloma Acuminatum-Reply. JAMA. 1984;251(8):1029. doi:10.1001/jama.1984.03340320018017
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