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March 2, 1984

Spontaneous Eradication of Adenocarcinoma Arising in a Colonic Polyp

Author Affiliations

Trinity Lutheran Hospital University of Missouri Kansas City

JAMA. 1984;251(9):1162. doi:10.1001/jama.1984.03340330024012

To the Editor.—Report of a Case.—  The patient was a 79-year-old man who experienced rectal bleeding for the first time at age 78 years. A barium enema examination disclosed multiple colonic polyps. There was a history of carcinoma of the colon in the patient's father, sister, and grandfather. One year later, the patient experienced a second episode of rectal bleeding and noticed a small piece of tissue with his feces. The tissue represented two fragments of polypoid mucosa that were 1.5 cm in greatest dimension and that contained areas of moderately differentiated adenocarcinoma. The patient thereafter underwent colonoscopy, which revealed the presence of at least ten pedunculated or sessile polyps, one of which demonstrated a friable area that may have been the source of the tissue retrieved. Gastroscopy and small-bowel roentgenography were done to attempt exclusion of another source for the adenocarcinoma, and these were normal. A colectomy with ileoproctostomy