—To assess the effects of physical exercise training on blood pressure in patients with mild hypertension.
—Randomized controlled trial.
—Hospital-based cardiac rehabilitation program.
—Ninety-nine men and women with untreated mild hypertension (systolic blood pressure, 140 to 180 mm Hg; diastolic blood pressure, 90 to 105 mm Hg) were included in the volunteer sample.
—Subjects were randomly assigned to a 4-month program of aerobic exercise training, strength and flexibility training, or to a waiting list control group.
Main Outcome Measures.
—The main outcome measures were systolic and diastolic blood pressures measured four times with a random zero sphygmomanometer on 3 separate days in a clinic setting.
—After 4 months of exercise training, subjects in the aerobic exercise group did not exhibit greater reductions in blood pressure than subjects in the control group. We expected a differential decline of 5 mm Hg between the aerobic exercise and waiting list control groups and found a difference of -1.0±16 mm Hg and -1.2±10 mm Hg at α=.05 for systolic and diastolic blood pressure, respectively.
—Moderate aerobic exercise alone should not be considered a replacement for pharmacologic therapy in nonobese patients with mild hypertension.(JAMA. 1991;266:2098-2104)
Blumenthal JA, Siegel WC, Appelbaum M. Failure of Exercise to Reduce Blood Pressure in Patients With Mild HypertensionResults of a Randomized Controlled Trial. JAMA. 1991;266(15):2098–2104. doi:10.1001/jama.1991.03470150070033