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July 13, 1984

A Cost-effectiveness Analysis of Alternative Approaches for Long-term Treatment of Proximal Venous Thrombosis

Author Affiliations

From the Departments of Medicine and Clinical Epidemiology and Biostatistics, Chedoke-McMaster Hospitals, Hamilton, Ontario, Canada.

JAMA. 1984;252(2):235-239. doi:10.1001/jama.1984.03350020037022

Recent data from randomized trials have provided a clear understanding of the effectiveness and safety of differing long-term anticoagulant therapies for proximal vein thrombosis. An issue that has not been addressed is their cost-effectiveness. We have performed a cost-effectiveness analysis to rank alternative approaches for long-term therapy. Less intense oral anticoagulant therapy using warfarin sodium is the most cost-effective approach and is preferred in the majority of patients.

(JAMA 1984;252:235-239)