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August 3, 1984

Possible platelet syndrome suggested in early stroke

JAMA. 1984;252(5):597-598. doi:10.1001/jama.1984.03350050005004

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Neurologists in Detroit have found a group of young patients with stroke whose ischemic events seem to be caused by platelets that aggregate too easily.

Some of these patients also have a history of migraine headaches and most come from families with histories of migraine headaches or early heart attacks and stroke. Treating these patients with a drug regimen that inhibits platelet aggregation and having them stop smoking cigarettes has proved to be successful therapy so far for preventing further strokes.

Young Patients and Sticky Platelets  These findings were reported at the Ninth International Joint Conference on Stroke and Cerebral Circulation, Tampa, Fla, by neurology resident Patti L. Holliday, MD, of the Wayne State University School of Medicine, Detroit. Holliday, fellow neurology resident John Buday, MD, and John Gilroy, MD, chair, Department of Neurology, have identified 15 persons between the ages of 9 and 47 years (mean age, 26 years)