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August 3, 1984

Gastrointestinal Disease: Pathophysiology, Diagnosis, Management

Author Affiliations

Hospital of the University of Pennsylvania Philadelphia

JAMA. 1984;252(5):690. doi:10.1001/jama.1984.03350050078037

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This is a welcome third edition to a textbook that has become a classic in gastroenterology. The book has ambitious aims, attempting to be a basic textbook for residents, fellows, practitioners, and gastroenterologists as well as providing current knowledge in pathophysiology to satisfy investigators as well as clinicians. It achieves its objectives in providing a thorough textbook of clinical gastroenterology and a concise but readable discussion of the basic science foundation of gastroenterology.

There have been major advances since 1978, when the last edition appeared, in many areas of gastroenterology, in the understanding of pathophysiology of disease states, in therapy available for diseases, and in the basic sciences. These advances have been covered well in this book, which has been reorganized. Many chapters are completely rewritten. The chapter on gastrointestinal (GI) tract hormones has been revised to discuss the role of these peptides both as neurotransmitters in the CNS and