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HAEMOPHIL US influenzae type b disease in young children may be starting to decline in the United States.
The newer conjugate vaccines may be a major factor. The picture probably will become more clear next spring.
A surveillance project by the Centers for Disease Control (CDC), Atlanta, Ga, so far has identified 50 cases of invasive H influenzae type b disease among children younger than 5 years. By comparison, over the same period in 1989, there were 176 cases.The first conjugate vaccines were licensed by the Food and Drug Administration in 1987. But vaccines were not available for children younger than 15 months until 1990.The surveillance system covers the San Francisco, Calif, and Atlanta metropolitan areas, the entire state of Oklahoma, and four counties in Tennessee. Every laboratory in these areas is contacted at regular intervals and all H influenzae isolates obtained.About 10.4 million people
Marwick C. Haemophilus influenzae Declining Among Young? JAMA. 1991;266(24):3398–3399. doi:10.1001/jama.1991.03470240020005
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