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November 23, 1984

Controversies in the Management of Lymphomas, Including Hodgkin's Disease

Author Affiliations

Harvard Medical School Brigham and Women's Hospital Boston

JAMA. 1984;252(20):2898. doi:10.1001/jama.1984.03350200066033

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Classification, diagnostic tools, and therapeutic alternatives for the malignant lymphomas present a fruitful field for research, as well as controversy, to the clinical investigator. This volume of Cancer Treatment and Research focuses on at least six major dilemmas in the study of Hodgkin's disease and non-Hodgkins lymphomas (NHLs).

The individually authored 13 chapters debate issues such as (1) What is the origin of the Reed-Sternberg cell? (2) Is lymphangiography a necessary procedure in staging or has it been totally replaced by computed tomography? (3) Is radiation therapy or chemotherapy or combination of radiation therapy and chemotherapy the best treatment for limited stages of Hodgkin's disease (stages I to III)? (4) Is Rappaport's classification of the NHLs useful for the clinician in deciding on therapy? (5) Is nodular mixed NHL a subset that is more favorably treated? and (6) Should "low grade" or "favorable" NHL be treated conservatively, aggressively, or not