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April 22, 1992

Initiating Trials

JAMA. 1992;267(16):2158. doi:10.1001/jama.1992.03480160016005

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PUTTING EMPHASIS on prevention, the American Cancer Society (1599 Clifton Rd NE, Atlanta, GA 30329) is studying if high-fiber diets will lower risk of colon cancer and low-fat diets will reduce breast cancer risk.

Walter Lawrence, Jr, MD, Medical College of Virginia (Commonwealth University), Richmond—president of the society—announced the research projects at the organization's 34th annual science writers seminar earlier this month in St Petersburg, Fla. Daniel Nixon, MD, a society vice president, is principal investigator.

Some 111 000 new cases of colon cancer are expected to be diagnosed in the United States this year, with about 51 000 deaths. New diagnoses of breast cancer are projected to be about 181000 with a death toll of about 46300.

The randomized, placebo-controlled, double-blind colon cancer trial hypothesizes that about 2000 patients experiencing one or more adenomatous polyps who adopt a fiber-supplemented diet will have fewer recurrent polyps. The 1980-patient two-phase breast