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August 26, 1992

Dietary Oat Fiber Sources and Blood Lipids

Author Affiliations

Atlanta, Ga

JAMA. 1992;268(8):985-986. doi:10.1001/jama.1992.03490080053022

To the Editor.—Cooper et al1 have recently reviewed the variations and practical utility of blood lipid measurements and have suggested that oat bran has only a modest cholesterol-lowering effect, and that dietary fiber grain supplements reduce cholesterol levels mainly because they replace dietary saturated fats. They base their conclusions primarily on a publication by Swain et al2; however, additional studies have since examined the relationships between dietary fiber, diet, and blood lipids, and have concluded that the cholesterol-lowering effects of fiber are not strictly a function of dietary substitution.3-5

Anderson et al3 studied 20 hypercholesterolemic men in the metabolic ward who were randomly allocated to either oat bran or wheat bran for 21 days after a 7-day control-diet period. Control and treatment diets were designed to be identical in energy content and nutrients, and differed only in the amount of soluble fiber. Oat bran significantly decreased