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October 11, 1985

Migration of Polytetrafluoroethylene—Polytef-Reply

Author Affiliations

Emory University School of Medicine Atlanta

JAMA. 1985;254(14):1903. doi:10.1001/jama.1985.03360140054013

In Reply.—  Although over 1,000 patients, both adult and children, have received periurethral injection of polytef paste, the Food and Drug Administration has approved the paste for one usage only—injection into the vocal cord. To our knowledge, the periurethral injection of polytef was first described in the literature by Berg1 in 1973. In his letter, Dr Politano discusses animal studies in dogs and guinea pigs, yet these studies have not been published. In case reports published by Dr Politano concerning his technique, the question of migration was not addressed or discussed until after our original article was presented at the 1983 national meeting of the American Urological Association.2 Had such migration been reported in the literature, there would have been no need for our study.Dr Politano further compares the migration of polytef particles with that of silicone particles from genitourinary prostheses. These comments are based on our unpublished