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October 25, 1985

Obstetrics and Gynecology

JAMA. 1985;254(16):2308-2309. doi:10.1001/jama.1985.03360160140037

Clinical research in obstetrics and gynecology holds considerable promise in the development of new techniques that will find broad application in clinical practice. Investigators in such diverse areas as prenatal diagnosis and gynecologic oncology are conducting clinical trials that may soon lead to earlier detection of congenital fetal anomalies and improved methods of administering cytotoxic agents in the treatment of neoplastic disease involving the female reproductive organs, particularly the ovary. A third area worthy of notice is the increasing acceptance and use of laser in the management of a variety of gynecologic conditions.

The role of amniocentesis in the prenatal evaluation of the fetus was described in CONTEMPO '82.1 This technique has become the standard of practice in the detection of a number of fetal anomalies, but it has certain drawbacks. The patient must wait until about the 16th week of pregnancy before the amniotic fluid can be sampled,