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December 6, 1985

Prevention of Estrogen-Induced Gynecomastia With Radiation Therapy

Author Affiliations

The Bowman Gray School of Medicine Wake Forest University Winston-Salem, NC

JAMA. 1985;254(21):3036. doi:10.1001/jama.1985.03360210050020

To the Editor.—  Although Dr Swillinger's1 question in the July 5 issue of JAMA specifically related to the necessity for mammography in a patient with gynecomastia secondary to estrogen therapy for prostate carcinoma, I feel that it is important to stress that gynecomastia can largely be prevented in these cases by irradiating each breast with up to 900 to 1,000 rad before estrogen therapy. This requires only three days for completion and prevents the hyperplasia that results in painful gynecomastia and should be considered by urologists prior to estrogen therapy.