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July 10, 1996

Incidence of HIV Infection in a New York City Methadone Maintenance Treatment Program

Author Affiliations

New York State Department of Health Albany
Beth Israel Medical Center New York, NY
Centers for Disease Control and Prevention Atlanta, Ga

JAMA. 1996;276(2):99. doi:10.1001/jama.1996.03540020021011

To the Editor.  —To estimate the incidence of human immunodeficiency virus (HIV) infection (seroconversions), a retrospective study of records from a voluntary HIV counseling and testing program at a New York City methadone maintenance treatment program (MMTP) was initiated. The study included records of patients who had 2 or more HIV tests and were HIV-negative on the initial test. A seroconverter was defined as a person with an initial HIV-negative test followed by an HIV-positive test. The seroconversion rate (incidence density of HIV infections) was calculated by dividing the number of seroconverters by the total number of personyears of follow-up. The follow-up time for nonseroconverters included the time between the initial test and the last test. For seroconverters, follow-up time was calculated as the midpoint between the last HIV-negative test and the first HIV-positive test.From July 1990 to April 1994, a total of 1833 voluntary HIV tests were conducted