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A MULTIDRUG-RESISTANT strain of Salmonella serotype Typhimurium known as Definitive Type 104 (DT104) has emerged as an increasing cause of Salmonella infections in the United Kingdom (UK). DT104 isolates in the UK are highly resistant to antimicrobial agents, frequently demonstrating a pattern of resistance to ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline (R-type ACSSuT).1 This report summarizes surveillance data documenting the rapid emergence of DT104 R-type ACSSuT in the United States and preliminary findings from the investigation of the first outbreak of DT104 infections in this country.
S. Typhimurium was the second most commonly reported Salmonella serotype in 1995, accounting for 9702 (24%) of 41222 Salmonella isolates reported that year. During July-August 1996, the algorithm used by the Public Health Laboratory Information System (PHLIS) to detect Salmonella outbreaks indicated that, in 29 states, the number of S. Typhimurium isolates had substantially increased when compared with a
Multidrug-Resistant Salmonella Serotype Typhimurium—United States, 1996. JAMA. 1997;277(19):1513. doi:10.1001/jama.1997.03540430025013
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