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May 28, 1997

Prognostic Implications of Elevated Creatine Kinase After Coronary Angioplasty

Author Affiliations

Sharon, Mass

JAMA. 1997;277(20):1593. doi:10.1001/jama.1997.03540440027020

To the Editor.  —Dr Kong and colleagues1 reported that elevation of CK following elective coronary artery intervention is associated with increased late cardiac mortality.1 Earlier reports of placebo-controlled animal studies with pretreatment with coenzyme Q10 (CoQ10)2,3 found that the animals pretreated with CoQ10 had less ischemia-reperfusion cardiac injury. They showed less myocardial tissue injury and lower CK and malondialdehyde release.