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August 18, 1883

ON A NEW METHOD OF OBTAINING PURE PANCREATIC JUICE.

JAMA. 1883;I(6):172-174. doi:10.1001/jama.1883.02390060012001c

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Abstract

[Read to the Section on Practice of Medicine, Materia Medica and Physiology, of Am. Med. Association, June, 1883.]

Physiologists are wont to employ one of two methods in obtaining pancreatic juice for purposes of experiment, viz., the method of Claude Bernard, and that of Ludwig and Bernstein. It is needless here to go into the details of either operation.

The method of Claude Bernard is open to the following objections:

1. Fixing, as it does, a temporary canula in the duct and collecting the secretion while the animal is under the shock of the operation, we can hardly assume the secretion to be normal.

2. This method offers but little opportunity for investigating variations in the character of the secretion dependent upon the period of digestion or upon the animal's diet.

The method of Ludwig and Bernstein is also open to objections, for:

1. The secretion of the fistulous tract

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