Mrs. F. W., a farmer's wife, always enjoyed good health. On Monday, September 27, 1875, about noon, she was attacked with headache, flushed, burning face, and expected a malarial chill. From that time the pain in the region of the frontal bone, at the root of the nose and below the eye, extending to the right ear, increased. At times the pain was more severe than at others, but never entirely left. These pains were described as dropping, tearing and boring, and so excruciating were they that at intervals, day and night, her cries could be heard at a great distance from the house. Tuesday evening bloody mucus began to run from the right nostril, which was some swollen. This swelling extended on Friday over the whole right side of the face. On this day, the fifth of the complaint, four larvæ dropped out of the right nostril. When I