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February 9, 1884

THE DISTRIBUTION OF THE POISON THROUGH THE BODY AFTER DEATH FROM ARSENIC.

JAMA. 1884;II(6):152-153. doi:10.1001/jama.1884.02390310012001a
Abstract

Some months ago we reported in this journal a series of experiments which showed the diffusion of arsenious acid through the body when suspended in water and injected into the mouth and rectum after death. We have to report some experiments on the distribution of the substance after fatal arsenical poisoning.

Has arsenic any predilection of tissue?

Scolosuboff,1 in 1875, reported that he had found, in experimenting upon animals, the largest amounts of the poison in the nervous tissue. He poisoned the animals with the arsenite of sodium, and after death estimated the amount of poison in 100 grams each of muscle, liver, brain and marrow. Representing the amount he found in the 100 grams of muscle by I, that found in the same amount of liver would be represented by 10.8, that in the brain by 36.5, and that in the marrow by 37.3. Scolosuboff supposed that the arsenic

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