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—Zweifel (Arch. für Gynack. Rev. Mensuelle des Maladies de l'Enfance,) asks if the ophthalmia of new-born infants may be produced by the normal utero-vaginal discharge (lochiæ), by the secretion furnished from catarrhal inflammation of these parts (leucorrhœa), or by a specific infectious agent (blennorrhagia). Neisser has described a special diplococcus gonorrhoæic which may be the microbe of blennorrhagia and which may be the cause of ophthalmia in the newly-born.
Zweifel has collected by the use of the pipette some of the lochiæ from the vaginæ of newly delivered women who were perfectly healthy, which under the microscope did not give any traces of the gonococcus and has inoculated this liquid into the conjunctivæ cul-de-sac of six new-born infants, but there followed no trace of inflammation or suppuration, and he arrives at the conclusion that, in order to have purulent ophthalmia in a new-born child there must be blennorrhagic inflammation
The Etiology of the Ophthalmia of New-born Infants.. JAMA. 1885;IV(6):156. doi:10.1001/jama.1885.02390810016006
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