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February 7, 1885


JAMA. 1885;IV(6):165. doi:10.1001/jama.1885.02390810025011

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Sedalia, Mo., Jan. 20, 1885.

Dear Journal:  —In your issue of 17th inst., I notice a communication from Dr. Leech, Jefferson Medical College, relating to ulcers of fingers. While I do not approve of charging everything of this nature to syphilitic virus, it would certainly appear that in the cases cited there must have been some specific poison, as the ophthalmitis of the infant would clearly show. The character of the ulceration, also, in my mind, would suggest animal poison. Our literature upon the subject of localized pustulations is fearfully meagre, so far as causation is concerned. Having just had a patient suffering in like manner, I was fearful of grave results. No cause could be attributed for the local trouble. I was treating the patient for a neurosis. The general health was good. The disease first manifested itself as a small blood-blister, about as large as a split pea,

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